Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Nephrotic syndrome
ADR ID BADD_A03027
ADR Hierarchy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.01      Glomerulonephritis and nephrotic syndrome
20.05.01.002      Nephrotic syndrome
Description A disorder characterized by symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. [CTCAE] Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA. [MeSH]
MedDRA Code 10029164
MeSH ID D009401; D009404; D009404
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Nephrosis | Nephrosis osmotic | Nephrotic syndrome | Nephrotic syndrome in diseases classified elsewhere | Nephrotic syndrome with lesion of membranoproliferative glomerulonephritis | Nephrotic syndrome with lesion of membranous glomerulonephritis | Nephrotic syndrome with lesion of minimal change glomerulonephritis | Nephrotic syndrome with lesion of proliferative glomerulonephritis | Nephrotic syndrome with other pathological lesion in kidney | Nephrotic syndrome with other specified pathological lesion in kidney | Nephrotic syndrome with unspecified pathological lesion in kidney | Syndrome nephrotic | Nephrotic syndrome worsened | Steroid-resistant nephrotic syndrome | Nephroses
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01508Mycophenolic acid0.001737%
BADD_D01511Nabumetone--
BADD_D01533Naproxen--
BADD_D01534Naproxen sodium--
BADD_D01567Nilotinib0.002398%
BADD_D01607Olsalazine--
BADD_D01608Olsalazine sodium--
BADD_D01614Omeprazole--
BADD_D01629Osimertinib0.000533%
BADD_D01635Oxaprozin--
BADD_D01661Pamidronate disodium--
BADD_D01662Pamidronic acid0.000564%
BADD_D01672Paraldehyde--
BADD_D01687Pazopanib0.008259%
BADD_D01709Penicillamine--
BADD_D01735Pergolide--
BADD_D01736Pergolide mesylate--
BADD_D01756Phentermine0.001234%
BADD_D01784Piroxicam--
BADD_D01834Prednisone0.000100%
BADD_D01835Pregabalin0.000826%
BADD_D01841Probenecid--
BADD_D01856Propafenone--
BADD_D01857Propafenone hydrochloride--
BADD_D01900Rabies virus immune globulin (human)--
BADD_D01909Ramipril0.000600%
BADD_D01911Ramucirumab--
BADD_D01922Regorafenib0.002398%
BADD_D01933Ribavirin0.081589%
BADD_D01940Rilpivirine--
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